Hey, yes you are right, if that is just a speaker then you would need a driver for it. The Qolsys panel siren output is just a relay to switch power to a low current siren. You could just replace the speaker with a siren, that would be the easiest.
PowerG sirens are compatible that are wireless.
You wouldn’t be able to tie in the Simplex system like that. The Hardwire 16F has one smoke zone for specific two wire smokes, and cannot otherwise accept fire devices.
I’m not finding documentation on the 4010-9911, but I am seeing it mentioned in 4010ES documentation.
Does it simply have a NC contact closure that trips whenever any fire event input occurs from the Simplex system?
There would be ways of monitoring that, though they would not be UL approved solutions.