does it sound right to keep them on different “loops”?
and/or what does it really mean
Yes. 345Mhz Honeywell and 2GIG sensors use Loops to differentiate between different sensor functions.
This is the same as if using a 2GIG Panel or Honeywell panel. If the wrong loop is entered, the panel will not be able to receive signals properly from that sensor.
Most sensors use Loop 1 as the main function, like Motion Detectors and Glass Breaks.
Multi-function devices have multiple loops. This will depend on the model of sensor. For example, the DW10 uses Loop 2 for its internal reed switch, and Loop 1 for its wired input.
For programming instructions for common 2GIG Sensors on the IQ Panel 2+ 345 Mhz version, see this page.